Asparagus Extract supplement health benefit, dosage
Review, side effects, capsules and tablets, research studies
Botanical name is Asparagus racemosus herb
February 28 2017

Roots of Asparagus racemosus are widely used in Ayurveda to stimulate the immune system, as a galactogogue (a food or medication or herb that promotes mother’s milk) and as a treatment of medical conditions such as ulcers and cancer. Asparagus racemosus has also been used successfully by some Ayurvedic practitioners for nervous disorders, inflammation, liver diseases and certain infectious diseases. Various studies have indicated immune system enhancement properties of Asparagus racemosus root extracts and formulations. This herb is known in India as Shatavari.

There is some preliminary information that this supplement may help liver health in those who drink heavily or may be helpful as a hangover remedy, but more research is needed.

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Asparagus Extract 270mg, 60 capsules
Purchase Asparagus Extract pill 60 Capsules
Asparagus extract Supplement Facts:
Serving Size 1 capsule
Asparagus (Asparagus officinalis) 270 mg
(10:1 Extract of root and leaf) 4% aspatagoside, asparagus stem.
10 to 1 extract, meaning the active ingredients are 10 times as concentrated as regular powder.

Recommendations: One asparagus capsule in the morning and lunch or as directed by your health care provider.

The root of Asparagus racemosus is widely used in the Ayurvedic system of medicine in India and is known for its steroidal saponin content. The root contains phytosterols, saponins, polyphenols, flavonoids and ascorbic acid. Saponins include shatavarins VI-X, shatavarin I (or asparoside B), shatavarin IV (or asparinin B), shatavarin V, immunoside and schidigerasaponin D5 (or asparanin A).
Racemoside A, B and C are water-soluble steroidal saponins purified from the fruits of Asparagus racemosus.

Human studies
We could not find any significant human studies with asparagus officinalis or asparagus racemosus as of 2017. The long term use of this dietary supplement appears to be safe based on anecdotal information, but until clinical studies are done we won’t know for certain.

Benefits of asparagus root extract
Asparagus racemosus is an important medicinal plant in India. Its medicinal value has been reported in the Indian and British Pharmacopoeias and in traditional systems of medicine such as Ayurveda, Unani and Siddha. Asparagus racemosus is mainly known for its phytoestrogenic properties. The herb is helpful in the treatment of neurodegenerative disorders and in alcohol abstinence-induced withdrawal symptoms. In Ayurveda, Asparagus racemosus has been described as a rasayana herb and has been used extensively as an adaptogen to increase the non-specific resistance of organisms against a variety of stresses. Besides use in the treatment of diarrhea and dysentery, the plant also has potent antioxidant, immune stimulating, anti-dyspepsia and antitussive effects.

Personal stories emailed to us, Testimonial
I am a 39 yo male and at New Year’s Eve I took 4 capsules of Advance Physician Formula Asparagus extract at 1 PM, and another 4 capsules around dinner time. I drank at least 5 shots of tequila and 3 vodka cranberries spread out between 8 pm to 1 am. My wife drove me home after the party. I woke up in the morning with no headache and no feeling of a hangover and I was up by 7 am on New Year’s day. I know my body, I am pretty sure if I had not taken the Physician Formulas supplement pills, I would have had a hangover and headache the next day.

Lipophilic phenolics content of asparagus root extract support its use as an antioxidant.

Suppression of reactive oxygen species and nitric oxide by Asparagus racemosus root extract using in vitro studies.
Cell Mol Biol (Noisy-le-grand). 2009; Visavadiya NP, Madamwar D. BRD School of Biosciences, Sardar Patel Maidan, Satellite Campus, Sardar Patel University, Vallabh Vidyanagar, Gujarat, India.
Recent clinical and experimental data showed the involvement of reactive oxygen species/nitrogen species (ROS) in many human pathophysiological conditions. Antioxidant activity of the extracts of Asparagus racemosus root were evaluated.  The addition of root extracts to human serum significantly reduced the formation of lipid peroxidation in medium. Trolox, alpha-tocopherol and mannitol were tested similarly to compare their antioxidant activities. In conclusion, antioxidant activity extract is effective. These effects are attributed to the high amount of lipophilic phenolics content of root extract.

The roots of Asparagus racemosus are popular for their aphrodisiac and immune enhancing properties. The herb has been traditionally used as Vajikaran Rasayana herb because of its positive influence on sexual performance in humans. Extracts obtained from the roots of Asparagus racemosus were studied for sexual behavior effects in male albino rats and compared with untreated control group animals. Administration of 200 mg/kg body weight of the aqueous extract had pronounced anabolic effect in treated animals as evidenced by weight gains in the body and reproductive organs. There was a significant variation in the sexual behavior of animals as reflected by reduction of mount latency, ejaculation latency, post ejaculatory latency, intromission latency, and an increase of mount frequency. Penile erection (indicated by Penile Erection Index) was also considerably enhanced. The observed effects appear to be attributable to the testosterone-like effects of the extracts. The present results, therefore, support the folklore claim for the usefulness of this herb and provides a scientific basis for its traditional usage. Archives of Sexual Behavior, 2009.

Clinical trials in humans will indicate whether his herb is helpful in treating depression.

Antidepressant activity of Asparagus racemosus in rodent models.
Pharmacol Biochem Behav. 2009; Singh GK, Garabadu D, Muruganandam AV, Krishnamurthy S. Pharmacology Division, Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi, India.
Although, the adaptogenic effect of Asparagus racemosus is well documented, its use in psychological disorders like depression is not scientifically evaluated. Hence, the present investigation evaluates the antidepressant effect of methanolic extract of roots of Asparagus racemosus standardized to saponins. Rats were given Asparagus racemosus extract for 7 days and then subjected to forced swim test and learned helplessness test. The results show that Asparagus extract decreases immobility in and increases avoidance response indicating antidepressant activity.  Asparagus extract has significant antidepressant activity and this effect is probably mediated through the serotonergic and the noradrenergic systems and augmentation of antioxidant defenses.

This herb may be useful for liver cancer.

The effect of the aqueous extract of the roots of Asparagus racemosus on hepatocarcinogenesis initiated by diethylnitrosamine.
Phytother Res. 2008; Agrawal A, Sharma M, Tiwari M, Chandra R. Dr B. R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi, India.
Histopathological studies of the hepatic tissues of Wistar rats treated with diethylnitrosamine once a week for 2 weeks, followed by treatment with DDT, a tumor promoter for 2 weeks and kept under observation for another 18 weeks, demonstrated the development of malignancy. Pretreatment of Wistar rats with the aqueous extract of the roots of Asparagus racemosus prevented the incidence of liver cancer. Our results prove that the aqueous extract of the roots of Asparagus racemosus has the potential to act as an effective formulation to prevent liver cancer induced by treatment with diethylnitrosamine.

High lipid levels and high cholesterol levels are major risk factors for atherosclerosis and cardiovascular diseases.

Asparagus Root Regulates Cholesterol Metabolism and Improves Antioxidant Status in Hypercholesteremic Rats.
Evid Based Complement Alternat Med. 2007. Visavadiya NP, Narasimhacharya AV. Department of Biosciences, Sardar Patel University, Vallabh Vidyanagar, Gujarat, India,
This study was designed to investigate the cholesterol lowering and antioxidant potential of Asparagus racemosus root in both normo- and hypercholesteremic animals. The results of the present study indicate that the potent therapeutic phyto-components present in Asparagus racemosus root i.e. phytosterols, saponins, polyphenols, flavonoids and ascorbic acid, could be responsible for increased bile acid production, elimination of excess cholesterol and elevation of hepatic antioxidant status in conditions of high cholesterol levels.

This herb may be helpful to those with gastric ulcer. Asparagus racemosus (Shatavari) is recommended in Ayurvedic texts for prevention and treatment of gastric ulcers, dyspepsia and as a galactogogue.

Antisecretory and antiulcer activity of Asparagus racemosus against indomethacin plus phyloric ligation-induced gastric ulcer in rats.
J Herb Pharmacother. 2006: Bhatnagar M, Sisodia SS. Department of Zoology, University College of Science, MLS University, Udaipur, India.
To study the antisecretory and antiulcer activity of Asparagus racemosus (methanolic extract) and its action against indomethacin (a non-steroidal anti-inflammatory drug) plus pyloric ligation induced gastric ulcers in rats. Asparagus racemosus was found to be an effective antiulcerogenic agent, whose activity can well be compared with that of ranitidine hydrochloride. The results of this study suggest that Asparagus racemosus causes an inhibitory effect on release of gastric hydrochloric acid and protects gastric mucosal damage.

Antiulcer and antioxidant activity of Asparagus racemosus and Withania somnifera Dunal in rats.
Ann N Y Acad Sci. 2005; Bhatnagar M, Sisodia SS, Bhatnagar R. Department of Zoology, University College of Science, Mohan Lal Sukhadia University, Udaipur, India.
Comparative study of the antiulcer and antisecretory activity of Asparagus racemosus (Shatawari) and Withania somnifera (Ashwagandha) root extract with a standard drug, ranitidine, in various models of gastric ulcer in rats is presented. Asparagus racemosus was more effective in reducing gastric ulcer in indomethacin-treated gastric ulcerative rats, whereas W. somnifera was effective in stress-induced gastric ulcer. Results obtained for both herbal drugs were comparable to those of the standard drug ranitidine.

Side effects, caution, risks, use during pregnancy, toxicity
Asparagus extract should not be used in pregnancy in high dosages. No major side effects have been reported in medical journals.

Teratogenicity of Asparagus racemosus root, a herbal medicine.
Indian J Exp Biol. 2006; Goel RK, Prabha T, Kumar MM, Dorababu M. Department of Anatomy, Institute of Medical Sciences, Banaras Hindu Univerisity, Varanasi, India.
Methanolic extract of Asparagus racemosus roots for 60 days showed teratological disorders in terms of increased resorption of fetuses, gross malformations e.g. swelling in legs and intrauterine growth retardation with a small placental size in Charles Foster rats. Pups born to mother exposed to Asparagus racemosus for full duration of gestation showed evidence of higher rate of resorption and therefore smaller litter size. Asparagus racemosus therefore, should be used in pregnancy cautiously as its exposure during that period may cause damage to the offspring.

Over the counter supplements and pills and capsules
Asparagus extract supplements are available in various dosages and extract potencies, and different species of asparagus. Here are some examples.

Asparagus officinalis 170 mg Rhizome Extract – Standardized to contain 4% asparagosides
A. officinalis Rhizome Extract standardized to contain 4% asparagosides 170 mg
Asparagus racemosus (root) Shataavari Dried water extract 500 mg
A. racemosus 500 mg standardized extract not less than 30% Sapponins + 350 mg micronised powder (Herb ratio 5:1) = 850 mg